Intravenous lipid emulsion for local anaesthetic systemic toxicity in pregnant women: a scoping review.

ABSTRACT:

Background

Local anaesthetic systemic toxicity (LAST) is a rare but life-threatening complication that can occur after local anaesthetic administration. Various clinical guidelines recommend an intravenous lipid emulsion as a treatment for local anaesthetic-induced cardiac arrest. However, its therapeutic application in pregnant patients has not yet been established. This scoping review aims to systematically identify and map the evidence on the efficacy and safety of intravenous lipid emulsion for treating LAST during pregnancy.

Method

We searched electronic databases (Medline, Embase and Cochrane Central Register Controlled Trials) and a clinical registry (lipidrescue.org) from inception to Sep 30, 2022. No restriction was placed on the year of publication or the language.

SUBMITTER: Tsuji M 

PROVIDER: S-EPMC10865663 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature