Microsporidia dressing up: the spore polaroplast transport through the polar tube and transformation into the sporoplasm membrane.

ABSTRACT: Microsporidia are obligate intracellular parasites that infect a wide variety of hosts including humans. Microsporidian spores possess a unique, highly specialized invasion apparatus involving the polar filament, polaroplast, and posterior vacuole. During spore germination, the polar filament is discharged out of the spore forming a hollow polar tube that transports the sporoplasm components including the nucleus into the host cell. Due to the complicated topological changes occurring in this process, the details of sporoplasm formation are not clear. Our data suggest that the limiting membrane of the nascent sporoplasm is formed by the polaroplast after microsporidian germination. Using electron microscopy and 1,1'-dioctadecyl-3,3,3',3' tetramethyl indocarbocyanine perchlorate staining, w

SUBMITTER: Lv Q 

PROVIDER: S-EPMC10865828 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature