Inflammatory Markers of Geriatric Depression Response to Tai Chi or Health Education Adjunct Interventions.

ABSTRACT:

Background

Underlying inflammation is associated with an increased risk of depression in older adults. In this study, we examined the role of inflammatory biomarkers in antidepressant response in depressed older adults undergoing adjunct Tai Chi Chih (TCC) or Health education interventions.

Methods

Older adults aged 60 years and above with a diagnosis of major depression were randomized to 12 weeks of TCC versus Health and Wellness Education (HEW) as an adjunct therapy to their stable antidepressant treatment regimen. A panel of 19 cytokine/chemokines was measured at baseline and 12 weeks. Five factors were derived using factor analysis. General linear models were estimated to examine the change in factor scores and the association of these changes on depression remission ra

SUBMITTER: Siddarth P 

PROVIDER: S-EPMC10865899 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature