Cost-effectiveness analysis of vaccination strategies against meningococcal disease for children under nine years of age in China.

ABSTRACT: Meningococcal vaccination strategies in China are intricate, including multiple vaccines targeting different serogroups. The current National Immunization Program (NIP) includes two polysaccharide vaccines for serogroups A and C (MPV-A and MPV-AC), covering limited serogroups and requiring adaptation. This study aims to evaluate the cost-effectiveness of replacing the current strategy with alternative strategies utilizing non-NIP vaccines to inform policy decisions. From a societal perspective, a decision tree-Markov model was constructed to simulate the economic and health consequences of meningococcal disease in a 2019 birth cohort with four vaccination strategies. Epidemiology, vaccine efficacy, cost, and other parameters were derived from previous studies. We conducted sensitivity anal

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10865926 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature