Proton Pump Inhibitors Use in Kidney Transplant Recipients: A Population-Based Study.

ABSTRACT:

Background

Kidney transplant recipients are commonly prescribed proton-pump inhibitors (PPIs), but due to concern for polypharmacy, chronic use should be limited.

Objective

The objective was to describe PPI use in kidney transplant recipients beyond their first year of transplant to better inform and support deprescribing initiatives.

Design

We conducted a retrospective, population-based cohort study using linked health care databases.

Setting

This study was conducted in Alberta, Canada.

Patients

We included all prevalent adult, kidney-only transplant recipients between April 2008 and December 2017 who received their transplant between May 2002 and December 2017.

Measurements

The primary outcome was ongoing or new PPI use and patterns of use, incl

SUBMITTER: Kiberd J 

PROVIDER: S-EPMC10865938 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature