Modular, multi-robot integration of laboratories: an autonomous workflow for solid-state chemistry.

ABSTRACT: Automation can transform productivity in research activities that use liquid handling, such as organic synthesis, but it has made less impact in materials laboratories, which require sample preparation steps and a range of solid-state characterization techniques. For example, powder X-ray diffraction (PXRD) is a key method in materials and pharmaceutical chemistry, but its end-to-end automation is challenging because it involves solid powder handling and sample processing. Here we present a fully autonomous solid-state workflow for PXRD experiments that can match or even surpass manual data quality, encompassing crystal growth, sample preparation, and automated data capture. The workflow involves 12 steps performed by a team of three multipurpose robots, illustrating the power of flexible,

SUBMITTER: Lunt AM 

PROVIDER: S-EPMC10866346 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature