Multimorbidity and frailty are associated with poorer SARS-CoV-2-related outcomes: systematic review of population-based studies.

ABSTRACT:

Background

Estimating the risks and impacts of COVID-19 for different health groups at the population level is essential for orienting public health measures. Adopting a population-based approach, we conducted a systematic review to explore: (1) the etiological role of multimorbidity and frailty in developing SARS-CoV-2 infection and COVID-19-related short-term outcomes; and (2) the prognostic role of multimorbidity and frailty in developing short- and long-term outcomes. This review presents the state of the evidence in the early years of the pandemic. It was conducted within the European Union Horizon 2020 program (No: 101018317); Prospero registration: CRD42021249444.

Methods

PubMed, Embase, World Health Organisation COVID-19 Global literature on coronavirus disease, and

SUBMITTER: Makovski TT 

PROVIDER: S-EPMC10866755 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature