A novel prognostic model of breast cancer based on cuproptosis-related lncRNAs.

ABSTRACT:

Objective

Breast cancer (BC) is a deadly form of malignancy responsible for the death of a large number of women every year. Cuproptosis is a newly discovered form of cell death that may have implications for the prognosis of BC. Long non-coding RNAs (lncRNAs) have been shown to be involved in the progression and development of BC. Here within, a novel model capable of predicting the prognosis of patients with BC was established based on cuproptosis-related lncRNAs.

Methods

Data of breast cancer patients was downloaded, including clinical information from The Cancer Genome Atlas (TCGA) database and lncRNAs related to cuproptosis were isolated. In total, nine lncRNAs related to copper death were obtained by Cox regression model based on Least Absolute Shrinkage and Selector O

SUBMITTER: Li F 

PROVIDER: S-EPMC10866837 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature