Effects of active vitamin D analogues on muscle strength and falls in elderly people: an updated meta-analysis.

ABSTRACT:

Background

Elderly people are at high risk of falls due to decreased muscle strength. So far, there is currently no officially approved medication for treating muscle strength loss. The active vitamin D analogues are promising but inconsistent results have been reported in previous studies. The present study was to meta-analyze the effect of active vitamin D analogues on muscle strength and falls in elderly people.

Methods

The protocol was registered with PROSPERO (record number: CRD42021266978). We searched two databases including PubMed and Cochrane Library up until August 2023. Risk ratio (RR) and standardized mean difference (SMD) with 95% confidence intervals (95% CI) were used to assess the effects of active vitamin D analogues on muscle strength or falls.

Results</

SUBMITTER: Xiong A 

PROVIDER: S-EPMC10867111 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature