The cardiomyopathy of cystic fibrosis: a modern form of Keshan disease.

ABSTRACT:

Introduction

We conducted a study to determine the prevalence of structural heart disease in patients with CF, the characteristics of a cardiomyopathy not previously described in this population, and its possible relationship with nutritional deficiencies in CF.

Methods

We studied 3 CMP CF patients referred for heart-lung transplantation and a prospective series of 120 adult CF patients. All patients underwent a clinical examination, blood tests including levels of vitamins and trace elements, and echocardiography with evaluation of myocardial strain. Cardiac magnetic resonance imaging (CMR) was performed in patients with CMP and in a control group. Histopathological study was performed on hearts obtained in transplant or necropsy.

Results

We found a prevalence of 10%

SUBMITTER: Segovia-Cubero J 

PROVIDER: S-EPMC10867141 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature