Global incidence of intrahepatic cholestasis of pregnancy: A protocol for systematic review and meta-analysis.

ABSTRACT:

Background

Intrahepatic cholestasis of pregnancy (ICP) typically develops in the late second and third trimesters and resolves rapidly after delivery. Although not associated with serious maternal sequelae, ICP can be highly bothersome. On the other hand, the major complications of ICP are fetal and neonatal, which can be fatal. The current knowledge lacks an estimation regarding the global prevalence of ICP.

Methods

PubMed, Scopus, and Web of Science will be searched systematically. Records will be screened for eligibility by two independent reviewers. Observational studies that reported the incidence of ICP will be eligible. Joanna Bridge Institute checklist for appraisal of prevalence studies will be used for quality assessment. Freeman-Tukey double arcsine transformed ef

SUBMITTER: Sadeghi A 

PROVIDER: S-EPMC10867694 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature