Challenging old microbiological treasures for natural compound biosynthesis capacity.

ABSTRACT: Strain collections are a treasure chest of numerous valuable and taxonomically validated bioresources. The Leibniz Institute DSMZ is one of the largest and most diverse microbial strain collections worldwide, with a long tradition of actinomycetes research. Actinomycetes, especially the genus Streptomyces, are renowned as prolific producers of antibiotics and many other bioactive natural products. In light of this, five Streptomyces strains, DSM 40971^T, DSM 40484^T, DSM 40713^T, DSM 40976^T, and DSM 40907^T, which had been deposited a long time ago without comprehensive characterization, were the subject of polyphasic taxonomic studies and genome mining for natural compounds based on in vitro and in silico analy

SUBMITTER: Nouioui I 

PROVIDER: S-EPMC10867783 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature