Physical activity and sleep pattern in relation to incident Parkinson's disease: a cohort study.

ABSTRACT:

Background

How physical activity (PA) and different sleep traits and overall sleep pattern interact in the development of Parkinson's disease (PD) remain unknown.

Objective

To prospectively investigate the joint associations of PA and sleep pattern with risk of PD.

Methods

Included were 339,666 PD-free participants from the UK Biobank. Baseline PA levels were grouped into low (< 600 MET-mins/week), medium (600 to < 3000 MET-mins/week) and high (≥ 3000 MET-mins/week) according to the instructions of the UK Biobank. Healthy sleep traits (chronotype, sleep duration, insomnia, snoring, and daytime sleepiness) were scored from 0 to 5 and were categorized into "ideal sleep pattern" (≥ 3 sleep scores) and "poor sleep pattern" (0-2 sleep scores). Hazard ratios (HRs) and 95% c

SUBMITTER: Chen LH 

PROVIDER: S-EPMC10867998 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature