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Serum fibroblast growth factor-2 levels complement vital biomarkers for diagnosing heart failure.


ABSTRACT:

Background

Early diagnosis of atrial fibrillation is important as it is crucial for improving patient outcomes. Fibroblast growth factor-2 (FGF2) may serve as a diagnostic biomarker for heart failure due to its ability to promote cardiac fibrosis and hypertrophy; however, the relationship between FGF2 concentration and heart failure is unclear. Therefore, this study aimed to explore whether FGF2 could aid in distinguishing patients with heart failure from healthy controls and those with dyspnea without heart failure. Additionally, to evaluate the possible correlation between serum FGF2 levels and its diagnostic parameters in patients with heart failure.

Methods

Plasma FGF2 concentration was measured in 114 patients with a complaint of dyspnea (enrolled in the study between J

SUBMITTER: Yu ZL 

PROVIDER: S-EPMC10868019 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature