Identifying cortical structure markers of resilience to adversity in young people using surface-based morphometry.

ABSTRACT: Previous research on the neurobiological bases of resilience in youth has largely used categorical definitions of resilience and voxel-based morphometry methods that assess gray matter volume. However, it is important to consider brain structure more broadly as different cortical properties have distinct developmental trajectories. To address these limitations, we used surface-based morphometry and data-driven, continuous resilience scores to examine associations between resilience and cortical structure. Structural MRI data from 286 youths (Mage = 13.6 years, 51% female) who took part in the European multi-site FemNAT-CD study were pre-processed and analyzed using surface-based morphometry. Continuous resilience scores were derived for each participant based on adversity exposure and leve

SUBMITTER: Cornwell H 

PROVIDER: S-EPMC10868125 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature