Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Draft genome sequence of Wigglesworthia glossinidia "palpalis gambiensis" isolate.

ABSTRACT: The 0.719 Mb genome of the tsetse endosymbiont, Wigglesworthia glossinidia, from Glossina palpalis gambiensis is presented. This Wigglesworthia genome retains 611 protein-coding sequences and a 25.3% GC content. A cryptic plasmid is conserved, between Wigglesworthia isolates, suggesting functional significance. This genome adds a further dimension to characterize Wigglesworthia lineage-based differences.

SUBMITTER: Spencer N

PROVIDER: S-EPMC10868223 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

Draft genome sequence of Wigglesworthia glossinidia "palpalis gambiensis" isolate.

Spencer Noah N Santee Mathilda M Wetherhold Adam A Rio Rita V M RVM

Microbiology resource announcements 20240111 2

The 0.719 Mb genome of the tsetse endosymbiont, Wigglesworthia glossinidia, from Glossina palpalis gambiensis is presented. This Wigglesworthia genome retains 611 protein-coding sequences and a 25.3% GC content. A cryptic plasmid is conserved, between Wigglesworthia isolates, suggesting functional significance. This genome adds a further dimension to characterize Wigglesworthia lineage-based differences. ...[more]

PMID: 38206026

Similar Datasets

Comparative gene expression of Wigglesworthia inhabiting non-infected and Trypanosoma brucei gambiense-infected Glossina palpalis gambiensis flies.

Project description:Tsetse flies (Glossina sp.) that transmit trypanosomes causing human (and animal) African trypanosomiasis (HAT and AAT, respectively) harbor symbiotic microorganisms, including the obligate primary symbiont Wigglesworthia glossinidia. A relationship between Wigglesworthia and tsetse fly infection by trypanosomes has been suggested, as removal of the symbiont results in a higher susceptibility to midgut infection in adult flies. To investigate this relationship and to decipher the role of W. glossinidia in the fly's susceptibility to trypanosome infection, we challenged flies with trypanosomes and subsequently analyzed and compared the transcriptomes of W. glossinidia from susceptible and refractory tsetse flies at three time points (3, 10, and 20 days). More than 200 W. glossinidia genes were found to be differentially expressed between susceptible and refractory flies. The high specificity of these differentially expressed genes makes it possible to distinguish Wigglesworthia inhabiting these two distinct groups of flies. Furthermore, gene expression patterns were observed to evolve during the infection time course, such that very few differentially expressed genes were found in common in Wigglesworthia from the 3-, 10- and 20-day post-feeding fly samples. The overall results clearly demonstrate that the taking up of trypanosomes by flies, regardless of whether flies proceed with the developmental program of Trypanosoma brucei gambiense, strongly alters gene expression in Wigglesworthia. These results therefore provide a novel framework for studies that aim to decrease or even abolish tsetse fly vector competence.

| S-EPMC4233935 | biostudies-literature

Glossina palpalis gambiensis

Project description:Glossina palpalis gambiensis Genome sequencing and assembly

| PRJNA172847 | ENA

Glossina palpalis gambiensis

Project description:Glossina palpalis gambiensis Transcriptome or Gene expression

| PRJNA176017 | ENA

Glossina palpalis gambiensis

Project description:Glossina palpalis gambiensis Transcriptome or Gene expression

| PRJNA260242 | ENA

Draft Genome Sequence of Riemerella anatipestifer Isolate 17CS0503.

Project description:Riemerella anatipestifer is a Gram-negative bacterium belonging to the family Flavobacteriaceae It is primarily associated with acute septicemia in younger birds. The R. anatipestifer isolate 17CS0503 described here was isolated from a Peking duck (Anas platyrhynchos domesticus) in Hannover, Germany, in 1999.

| S-EPMC5958266 | biostudies-literature

Draft Genome Sequence of a Primate Isolate of Kazachstania pintolopesii.

Project description:Kazachstania pintolopesii is an opportunistic mammalian pathobiont from the K. telluris species complex. No draft genomes of this species are currently available. Here, we report the first draft genome sequence of a primate isolate of K. pintolopesii (NCYC 4417).

| S-EPMC10564811 | biostudies-literature

Draft Genome Sequence of Clinical Isolate Alcaligenaceae sp. Strain 429.

Project description:Here, we present the 3.53-Mb genome for Alcaligenaceae sp. strain 429, isolated from a patient with unknown etiology. While the 16S rRNA gene most closely resembles Paenalcaligenes species, average amino acid identity (AAI) analysis did not meet the threshold to classify our strain as a species of this family.

| S-EPMC6509538 | biostudies-literature

Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate.

Project description:We report the draft genome sequence of a vaginal isolate of Atopobium vaginae vaginae (strain 44061), an organism linked to bacterial vaginosis (BV), the most common gynecological infection in the United States. This species is often highly resistant to metronidazole, which is a front-line therapy for BV. Strain 44061 is a metronidazole-susceptible isolate (MIC, 16 µg/ml), and its genome sequence will be useful for comparative studies to elucidate the molecular basis of metronidazole resistance in this species.

| S-EPMC4559735 | biostudies-literature

Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate.

Project description:We report the draft genome sequence of a Gardnerella vaginalis strain (3549624) isolated from a vaginal specimen. G. vaginalis is associated with bacterial vaginosis, the most common cause of vaginal discharge, which is often treated with metronidazole. This isolate is highly resistant to metronidazole (MIC, 500 µg/ml) and may be useful for comparative genomic studies to determine the molecular basis of metronidazole resistance in this species.

| S-EPMC4559736 | biostudies-literature

Draft Genome Sequence of the Bordetella bronchiseptica Swine Isolate KM22.

Project description:Bordetella bronchiseptica swine isolate KM22 has been used in experimental infections of swine as a model of clinical B. bronchiseptica infections within swine herds and to study host-to-host transmission. Here we report the draft genome sequence of KM22.

| S-EPMC4110755 | biostudies-literature