Sleep and motor learning in stroke (SMiLES): a longitudinal study investigating sleep-dependent consolidation of motor sequence learning in the context of recovery after stroke.

ABSTRACT:

Introduction

There is growing evidence that sleep is disrupted after stroke, with worse sleep relating to poorer motor outcomes. It is also widely acknowledged that consolidation of motor learning, a critical component of poststroke recovery, is sleep-dependent. However, whether the relationship between disrupted sleep and poor outcomes after stroke is related to direct interference of sleep-dependent motor consolidation processes, is currently unknown. Therefore, the aim of the present study is to understand whether measures of motor consolidation mediate the relationship between sleep and clinical motor outcomes post stroke.

Methods and analysis

We will conduct a longitudinal observational study of up to 150 participants diagnosed with stroke affecting the upper limb. Part

SUBMITTER: Weightman M 

PROVIDER: S-EPMC10868290 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature