Pooling of primary care electronic health record (EHR) data on Huntington's disease (HD) and cancer: establishing comparability of two large UK databases.

ABSTRACT:

Objectives

To explore whether UK primary care databases arising from two different software systems can be feasibly combined, by comparing rates of Huntington's disease (HD, which is rare) and 14 common cancers in the two databases, as well as characteristics of people with these conditions.

Design

Descriptive study.

Setting

Primary care electronic health records from Clinical Practice Research Datalink (CPRD) GOLD and CPRD Aurum databases, with linked hospital admission and death registration data.

Participants

4986 patients with HD and 1 294 819 with an incident cancer between 1990 and 2019.

Primary and secondary outcome measures

Incidence and prevalence of HD by calendar period, age group and region, and annual age-standardised incidence of 14 common

SUBMITTER: Dedman D 

PROVIDER: S-EPMC10868307 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature