Efficacy and safety of raltitrexed-eluting CalliSpheres^® bead transarterial chemoembolization in patients with intermediate-stage hepatocellular carcinoma: a single-arm, prospective study.

ABSTRACT:

Background

The most common loadable chemotherapeutic drugs in drug-eluting bead transarterial chemoembolization (DEB-TACE) include doxorubicin, epirubicin, etc. CalliSpheres^® beads have exhibited efficient loadability and eluting characteristics for raltitrexed as well as in vitro and animal experiments. However, the efficacy and safety of raltitrexed-loaded DEB-TACE in patients with intermediate-stage hepatocellular carcinoma (HCC) remain unclear.

Objectives

To assess the efficacy and safety of raltitrexed-loaded DEB-TACE in patients with intermediate-stage HCC.

Design

The study was conducted as a single-arm prospective study.

Methods

This study was a prospective, single-arm trial conducted between June 2019 and June 2022. CalliSpheres^®<

SUBMITTER: Sun Z 

PROVIDER: S-EPMC10868504 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature