Modeling of cryopreservation pathway operation at an aquatic biomedical stock center for zebrafish.

ABSTRACT: Aquatic biomedical model organisms play a substantial role in advancing our understanding of human health, however, comparably little work has been directed towards developing dependable, high-throughput storage programs for valuable genetic resources. The Zebrafish International Resource Center (ZIRC) has developed a standardized cryopreservation pathway and stored thousands of genetic lines in their repository for use by the biomedical research community. This has yet to be replicated in other facilities, and an overall repository-level pathway has never been analyzed for aquatic species. To encourage repository development for other biomedical models and to improve the ZIRC storage process and system, this study used discrete-event simulation modeling to systematically analyze the cryop

SUBMITTER: Bodenstein S 

PROVIDER: S-EPMC10868577 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature