Genomic epidemiology of the clinically dominant clonal complex 1 in the Listeria monocytogenes population in the UK.

ABSTRACT: Listeria monocytogenes is a food-borne pathogen, typically affecting the elderly, immunocompromised patients and pregnant women. The aim of this study was to determine the population structure of L. monocytogenes clonal complex 1 (CC1) in the UK and describe the genomic epidemiology of this clinically significant CC. We interrogated a working dataset of 4073 sequences of L. monocytogenes isolated between January 2015 and December 2020 from human clinical specimens, food and/or food-production environments. A minimum spanning tree was reconstructed to determine the population structure of L. monocytogenes in the UK. Subsequent analysis focused on L. monocytogenes CC1, as the cause of the highest proportion of invasive listeriosis in humans. Sequencing data

SUBMITTER: Fotopoulou ET 

PROVIDER: S-EPMC10868620 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature