Preventing iatrogenic HCV infection: A quantitative risk assessment based on observational data in an Egyptian hospital.

ABSTRACT: When compliance with infection control recommendations is non-optimal, hospitals may play an important role in hepatitis C (HCV) transmission. However, few studies have analyzed the nosocomial HCV acquisition risk based on detailed empirical data. Here, we used data from a prospective cohort study conducted on 500 patients in the Ain Shams hospital (Cairo, Egypt) in 2017 with the objective of identifying (i) high-risk patient profiles and (ii) transmission hotspots within the hospital. Data included information on patient HCV status upon admission, their trajectories between wards and the invasive procedures they underwent. We first performed a sequence analysis to identify different hospitalization profiles. Second, we estimated each patient's individual risk of HCV acquisition based on w

SUBMITTER: Henriot P 

PROVIDER: S-EPMC10868760 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature