Antioxidant and antiproliferative effect of a glycosaminoglycan extract from Rapana venosa marine snail.

ABSTRACT: Marine glycosaminoglycans (GAG) isolated from different invertebrates, such as molluscs, starfish or jellyfish, have been described as unique molecules with important pharmacological applications. Scarce information is available on GAG extract from Rapana venosa marine snail. The aim of this study was to isolate a GAG extract from R. venosa marine snail and to investigate its physicochemical, antioxidant and antiproliferative properties for further biomedical use. The morphology, chemical and elemental composition of the extract were established as well as the sulfate content and N- to O-sulfation ratio. Fourier transform infrared (FTIR) spectra indicated that GAG extract presented similar structural characteristics to bovine heparan sulfate and chondroitin sulfate. The pattern of extract

SUBMITTER: Gaspar-Pintiliescu A 

PROVIDER: S-EPMC10868805 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature