The synergistic effect of herbal medicine and probiotics in pediatric functional constipation: A systematic review and meta-analysis.

ABSTRACT:

Background

Pediatric functional constipation (PFC) is a prevalent and persistent gastrointestinal disorder, that requires various treatments, including alternative approaches. This review assessed the synergistic efficacy of herbal medicine (HM) and probiotics for PFC.

Methods

We conducted a comprehensive search of 11 databases, including English, Chinese, and Korean databases, until June 29, 2023. The inclusion criteria were randomized clinical trials (RCTs) comparing the intervention of HM with probiotics to that of the same probiotics. Statistical analyses included calculation of the mean difference (MD), standardized MD, risk ratio (RR) with a 95% confidence interval (CI), and assessment of risk of bias using Review Manager Version 5.4 software. The Grading of Recommenda

SUBMITTER: Kim E 

PROVIDER: S-EPMC10869098 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature