Exercise training outcomes in patients with chronic heart failure with reduced ejection fraction depend on patient background.

ABSTRACT:

Background

The aim of this study was to identify significant factors affecting the effectiveness of exercise training using information of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) study.

Methods

Background factors influencing the effect of exercise training were comprehensively surveyed for 2,130 patients by multivariable Cox regression analysis with the stepwise variable selection, and only significant factors were selected that were statistically distinguished from dummy noise factors using the Boruta method.

Results

The analysis suggested that the use of beta-blockers, pulse pressure, hemoglobin level, electrocardiography findings, body mass index, and history of stroke at baseline potentially influenced the exer

SUBMITTER: Soejima Y 

PROVIDER: S-EPMC10869166 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature