Understanding the differential impacts of two antidepressants on locomotion of freshwater snails (Lymnaea stagnalis).

ABSTRACT: There is growing evidence of negative impacts of antidepressants on behavior of aquatic non-target organisms. Accurate environmental risk assessment requires an understanding of whether antidepressants with similar modes of action have consistent negative impacts. Here, we tested the effect of acute exposure to two antidepressants, fluoxetine and venlafaxine (0-50 µg/L), on the behavior of non-target organism, i.e., freshwater pond snail, Lymnaea stagnalis. As compounds interact with chemical cues in the aquatic ecosystems, we also tested whether the effects altered in the presence of bile extract containing 5α-cyprinol sulfate (5α-CPS), a characterized kairomone of a natural predator, common carp (Cyprinus carpio). Behavior was studied using automated tracking and analysis of various loco

SUBMITTER: Raman NV 

PROVIDER: S-EPMC10869440 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature