Quantitative measurements of reactive oxygen species partitioning in electron transfer flavoenzyme magnetic field sensing.

ABSTRACT: Biological magnetic field sensing that gives rise to physiological responses is of considerable importance in quantum biology. The radical pair mechanism (RPM) is a fundamental quantum process that can explain some of the observed biological magnetic effects. In magnetically sensitive radical pair (RP) reactions, coherent spin dynamics between singlet and triplet pairs are modulated by weak magnetic fields. The resulting singlet and triplet reaction products lead to distinct biological signaling channels and cellular outcomes. A prevalent RP in biology is between flavin semiquinone and superoxide (O₂ ^•-) in the biological activation of molecular oxygen. This RP can result in a partitioning of reactive oxygen species (ROS) products to form either O₂ ^•-<

SUBMITTER: Austvold CK 

PROVIDER: S-EPMC10869518 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature