Catheter-associated bladder mucosal trauma during intermittent voiding: An experimental study in pigs.

ABSTRACT:

Objective

The objective of this study is to characterize bladder mucosal trauma associated with intermittent catheterization with conventional eyelet catheters (CECs) and to assess if a microhole zone catheter (MHZC) design concept reduces this adverse effect.

Materials and methods

A porcine model was developed to reflect human catheterization and bladder drainage. Nine pigs were randomized for catheterization with CEC (n = 6) or MHZC (n = 3). The bladder was drained repeatedly 20 times through the catheter. Cystoscopy was performed before and after the procedure, and bladders were analysed by histopathology. Two additional pigs were used for cystoscopy visualization of suction events in vivo. Cystoscopy, gross pathology, histopathological score, leucocyte infi

SUBMITTER: Stærk K 

PROVIDER: S-EPMC10869658 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature