Molecular epidemiology and clinical impact of Klebsiella spp. causing bloodstream infections in Hong Kong.

ABSTRACT:

Background

The epidemiological features of the Klebsiella pneumoniae causing bloodstream infections in Hong Kong and their potential threats to human health remained unknown.

Methods

K. pneumoniae strains collected from four hospitals in Hong Kong during the period of 2009-2018 were subjected to molecular typing, string test, antimicrobial susceptibility testing, whole genome sequencing and analysis. Clinical data of patients from whom these strains were isolated were analyzed retrospectively using univariate and multivariate logistic regression approaches.

Findings

The 240 Klebsiella spp. strains belonged to 123 different STs and 63 different capsule loci (KLs), with KL1 and KL2 being the major type. 86 out of 212 BSI-KP (40.6%) carried at least one of the virulence

SUBMITTER: Yang X 

PROVIDER: S-EPMC10869758 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature