Prehospital optimal shock energy for defibrillation (POSED): A cluster randomised controlled feasibility trial.

ABSTRACT:

Background

We explored the feasibility of a large-scale UK ambulance services trial of optimal defibrillation shock energy for out-of-hospital cardiac arrest. The primary objective of this feasibility study was to establish the number of eligible patients and the number recruited. Secondary outcomes were adherence to allocated treatment and data completeness.

Methods

We conducted a three-arm parallel group cluster randomised controlled feasibility study in a single ambulance service in southern England. Adult patients in out-of-hospital cardiac arrest treated for a shockable rhythm were included. Zoll X series defibrillators (clusters) were randomised to deliver 120-150-200 J, 150-200-200 J, or 200-200-200 J shock strategies.

Results

Between March 2022 and February 20

SUBMITTER: Pocock H 

PROVIDER: S-EPMC10869912 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature