Nonadditivity in interactions between three membrane-wrapped colloidal spheres.

ABSTRACT: Many cell functions require a concerted effort from multiple membrane proteins, for example, for signaling, cell division, and endocytosis. One contribution to their successful self-organization stems from the membrane deformations that these proteins induce. While the pairwise interaction potential of two membrane-deforming spheres has recently been measured, membrane-deformation-induced interactions have been predicted to be nonadditive, and hence their collective behavior cannot be deduced from this measurement. We here employ a colloidal model system consisting of adhesive spheres and giant unilamellar vesicles to test these predictions by measuring the interaction potential of the simplest case of three membrane-deforming, spherical particles. We quantify their interactions and arrang

SUBMITTER: Azadbakht A 

PROVIDER: S-EPMC10870171 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature