Rare neurodevelopmental conditions and parents' mental health - how and when does genetic diagnosis matter?

ABSTRACT:

Background

Parents of individuals with rare neurodevelopmental conditions and intellectual disabilities (ID) are vulnerable to mental health difficulties, which vary between parents and within parents over time. The underlying cause of a child's condition can influence parents' mental health, via uncertain pathways and within unknown time-windows.

Results

We analysed baseline data from the IMAGINE-ID cohort, comprising 2655 parents of children and young people with ID of known genetic origin. First, we conducted a factor analysis of the SDQ Impact scale to isolate specific pathways from genetic aetiology to parents' mental health. This suggested a two-factor structure for the SDQ Impact scale, with a "home & distress" dimension and a "participation" dimension. Second, we tes

SUBMITTER: Chi Z 

PROVIDER: S-EPMC10870533 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature