Vinylic C-H Activation of Styrenes by an Iron-Aluminum Complex.

ABSTRACT: The oxidative addition of sp² C-H bonds of alkenes to single-site transition-metal complexes is complicated by the competing π-coordination of the C═C double bond, limiting the examples of this type of reactivity and onward applications. Here, we report the C-H activation of styrenes by a well-defined bimetallic Fe-Al complex. These reactions are highly selective, resulting in the (E)-β-metalation of the alkene. For this bimetallic system, alkene binding appears to be essential for the reaction to occur. Experimental and computational insights suggest an unusual reaction pathway in which a (2 + 2) cycloaddition intermediate is directly converted into the hydrido vinyl product via an intramolecular sp² C-H bond activation across the two metals. The key C-

SUBMITTER: Gorgas N 

PROVIDER: S-EPMC10870711 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature