Phase-Incremented Steady-State Free Precession as an Alternate Route to High-Resolution NMR.

ABSTRACT: Pulsed Fourier transform nuclear magnetic resonance (FT-NMR) has reigned supreme in high-resolution, high-field spectroscopy─particularly when targeting complex liquid-state samples involving multiple sharp peaks spread over large spectral bandwidths. It is known, however, that if spectral resolution is not a must, the FT-based approach is not necessarily the optimal route for maximizing NMR sensitivity: if T₂ ≈ T₁, as often found in solutions, Carr's steady-state free-precession (SSFP) approach can in principle provide a superior signal-to-noise ratio per √(acquisition_time) (SNR_t). A rapid train of pulses will then lead to a transverse component that reaches up to 50% of the thermal equilibrium magnetization, provided that pulses are applied

SUBMITTER: He T 

PROVIDER: S-EPMC10870713 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature