Association of left ventricular diastolic function with coronary artery calcium score: A Project Baseline Health Study.

ABSTRACT:

Background

Coronary artery calcium (CAC) and left ventricular diastolic dysfunction (LVDD) are strong predictors of cardiovascular events and share common risk factors. However, their independent association remains unclear.

Methods

In the Project Baseline Health Study (PBHS), 2082 participants underwent cardiac-gated, non-contrast chest computed tomography (CT) and echocardiography. The association between left ventricular (LV) diastolic function and CAC was assessed using multidimensional network and multivariable-adjusted regression analyses. Multivariable analysis was conducted on continuous LV diastolic parameters and categorical classification of LVDD and adjusted for traditional cardiometabolic risk factors. LVDD was defined using reference limits from a low-risk refe

SUBMITTER: Haddad F 

PROVIDER: S-EPMC10870833 | biostudies-literature | 2022 Nov-Dec

REPOSITORIES: biostudies-literature