Ambient traffic related air pollution in relation to ovarian reserve and oocyte quality in young, healthy oocyte donors.

ABSTRACT: Studies in mice and older, subfertile women have found that air pollution exposure may compromise female reproduction. Our objective was to evaluate the effects of air pollution on ovarian reserve and outcomes of ovarian stimulation among young, healthy females. We included 472 oocyte donors who underwent 781 ovarian stimulation cycles at a fertility clinic in Atlanta, Georgia, USA (2008-2019). Antral follicle count (AFC) was assessed with transvaginal ultrasonography and total and mature oocyte count was assessed following oocyte retrieval. Ovarian sensitivity index (OSI) was calculated as the total number of oocytes divided by total gonadotrophin dose × 1000. Daily ambient exposure to nitric oxide (NO_x), carbon monoxide (CO), and particulate matter ≤ 2.5 (PM_2.5) was

SUBMITTER: LaPointe S 

PROVIDER: S-EPMC10871039 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature