Identification of patients with favorable prognosis after resection in intermediate-stage-hepatocellular carcinoma.

ABSTRACT:

Backgrounds

It is unclear which patients benefit from resection in intermediate-stage-hepatocellular carcinoma (HCC). The authors aimed to identify high-risk patients for early recurrence among patients with resectable intermediate-stage HCC.

Methods

This multicenter retrospective study included patients who underwent resection or trans-arterial chemoembolization (TACE) for intermediate-stage HCC (2008-2019). Multivariable Cox proportional analysis was performed to identify high-risk patients when treated with resection. A prediction score for 2-year recurrence-free survival (RFS) was developed using the training cohort and validated. The 2-year RFS in each risk group was compared with that in TACE group, after propensity score matching (PSM).

Results

A total of 1686

SUBMITTER: Lee HA 

PROVIDER: S-EPMC10871631 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature