Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial.

ABSTRACT:

Context and objective

Neuromodulation techniques for treating obsessive-compulsive disorder (OCD) have expanded through greater understanding of the brain circuits involved in this disorder. Transcranial direct current stimulation (tDCS), a non-invasive technique, has been studied as an alternative for treatment-resistant OCD. We describe the design of a clinical trial using tDCS for OCD and report on the outcomes from two patients with primary OCD who were resistant to cognitive-behavioral therapy and to selective serotonin reuptake inhibitors, and who received tDCS in an open manner during the training phase for the study procedures.

Design and setting

Methodological description of a clinical trial using tDCS for treatment-resistant OCD at a university hospital; and a repo

SUBMITTER: Silva RM 

PROVIDER: S-EPMC10871858 | biostudies-literature | 2016 Sep-Oct

REPOSITORIES: biostudies-literature