Plasma concentrations of histidine-rich glycoprotein in primary graft dysfunction after lung transplantation.

ABSTRACT:

Objectives

Histidine-rich glycoprotein has been reported as an anti-inflammatory glycoprotein that inhibits acute lung injury in mice with sepsis and as a prognostic biomarker in patients with sepsis. We investigated the relationship between plasma concentrations of histidine-rich glycoprotein and the risk of occurrence of primary graft dysfunction.

Methods

According to the primary graft dysfunction grade at post-transplant 72 h, patients who underwent lung transplantation were divided into three groups: non-primary graft dysfunction group (grade 0-1), moderate primary graft dysfunction group (grade 2), and severe primary graft dysfunction group (grade 3). The plasma concentrations of histidine-rich glycoprotein measured daily during the first post-transplant 7 days were com

SUBMITTER: Shiotani T 

PROVIDER: S-EPMC10871901 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature