Mechanism of Alkene Hydrofunctionalization by Oxidative Cobalt(salen) Catalyzed Hydrogen Atom Transfer.

ABSTRACT: Oxidative MHAT hydrofunctionalization of alkenes provides a mild cobalt-catalyzed route to forming C-N and C-O bonds. Here, we characterize relevant salen-supported cobalt complexes and their reactions with alkenes, silanes, oxidant, and solvent. These stoichiometric investigations are complemented by kinetic studies of the catalytic reaction and catalyst speciation. We describe the solution characterization of an elusive cobalt(III) fluoride complex, which surprisingly is not the species that reacts with silane under catalytic conditions; rather, a cobalt(III) aquo complex is more active. Accordingly, the addition of water (0.15 M) speeds the catalytic reaction, and kinetic studies show that water addition enables catalytic product formation in 2 h at -50 °C in acetone. Under these

SUBMITTER: Wilson CV 

PROVIDER: S-EPMC10872242 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature