A Biotinylated Glycosylphosphatidylinositol (GPI) as the Universal Platform To Access GPI-Anchored Protein Analogues.
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ABSTRACT:
SUBMITTER: Yan X
PROVIDER: S-EPMC10872333 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
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A Biotinylated Glycosylphosphatidylinositol (GPI) as the Universal Platform To Access GPI-Anchored Protein Analogues.
Yan Xin X Guo Jiatong J Kundu Sayan S Guo Zhongwu Z
The Journal of organic chemistry 20231228 2
A glycosylphosphatidylinositol (GPI) derivative with biotin linked to its mannose III 6-O-position was prepared by a convergent strategy. This biotinylated GPI was demonstrated to bind avidinated proteins readily through biotin-avidin interaction and, therefore, can serve as a universal platform to access various biologically significant GPI-anchored protein analogues. ...[more]
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