2D or not 2D? Mapping the in-depth inclination of the collagen fibers of the corneoscleral shell.

ABSTRACT: The collagen fibers of the corneoscleral shell play a central role in the eye mechanical behavior. Although it is well-known that these fibers form a complex three-dimensional interwoven structure, biomechanical and microstructural studies often assume that the fibers are aligned in-plane with the tissues. This is convenient as it removes the out-of-plane components and allows focusing on the 2D maps of in-plane fiber organization that are often quite complex. The simplification, however, risks missing potentially important aspects of the tissue architecture and mechanics. In the cornea, for instance, fibers with high in-depth inclination have been shown to be mechanically important. Outside the cornea, the in-depth fiber orientations have not been characterized, preventing a deeper unders

SUBMITTER: Ji F 

PROVIDER: S-EPMC10872428 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature