A precision neuroscience approach to estimating reliability of neural responses during emotion processing: Implications for task-fMRI.

ABSTRACT: Recent work demonstrating low test-retest reliability of neural activation during fMRI tasks raises questions about the utility of task-based fMRI for the study of individual variation in brain function. Two possible sources of the instability in task-based BOLD signal over time are noise or measurement error in the instrument, and meaningful variation across time within-individuals in the construct itself-brain activation elicited during fMRI tasks. Examining the contribution of these two sources of test-retest unreliability in task-evoked brain activity has far-reaching implications for cognitive neuroscience. If test-retest reliability largely reflects measurement error, it suggests that task-based fMRI has little utility in the study of either inter- or intra-individual differences. On

SUBMITTER: Flournoy JC 

PROVIDER: S-EPMC10872443 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature