Intravenous Ketorolac Substantially Reduces Opioid Use and Length of Stay After Lumbar Fusion: A Randomized Controlled Trial.

ABSTRACT:

Study design

A randomized, double-blinded, placebo-controlled trial.

Objective

To examine the effect of intravenous ketorolac (IV-K) on hospital opioid use compared with IV-placebo (IV-P) and IV acetaminophen (IV-A).

Summary of background data

Controlling postoperative pain while minimizing opioid use after lumbar spinal fusion is an important area of study.

Patients and methods

Patients aged 18 to 75 years undergoing 1 to 2 level lumbar fusions between April 2016 and December 2019 were included. Patients with chronic opioid use, smokers, and those on systemic glucocorticoids or contraindications to study medications were excluded. A block randomization scheme was used, and study personnel, hospital staff, and subjects were blinded to the assignment. Patients w

SUBMITTER: Iyer S 

PROVIDER: S-EPMC10872662 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature