In-utero exposure to polybrominated biphenyl (PBB) and menstrual cycle function in adulthood.

ABSTRACT:

Background

There is evidence that in-utero exposure to PBBs, and similar chemicals, are associated with several adverse reproductive health outcomes including altered pubertal timing. However, less is known about the effects of in-utero exposure to PBBs on menstrual cycle function and reproductive hormone levels in adulthood.

Methods

For this menstrual cycle study, we recruited reproductive-aged women in the Michigan PBB Registry who were not pregnant, lactating, or taking hormonal medications (2004-2014). A total of 41 women who were born after the PBB contamination incident (1973-1974) and were prenatally exposed to PBBs, were included in this analysis. We estimated in-utero PBB exposure using maternal serum PBB measurements taken after exposure and extrapolated to time of

SUBMITTER: Barat S 

PROVIDER: S-EPMC10872753 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature