Validation of single reference variable flip angle (SR-VFA) dynamic T₁ mapping with T₂ * correction using a novel rotating phantom.

ABSTRACT:

Purpose

To validate single reference variable flip angle (SR-VFA) dynamic T₁ mapping with and without T₂ * correction against inversion recovery (IR) T₁ measurements.

Methods

A custom cylindrical phantom with three concentric compartments was filled with variably doped agar to produce a smooth spatial gradient of the T₁ relaxation rate as a function of angle across each compartment. IR T₁ , VFA T₁ , and B₁ ⁺ measurements were made on the phantom before rotation, and multi-echo stack-of-radial dynamic images were acquired during rotation via an MRI-compatible motor. B₁ ⁺ -corrected SR-VFA and SR-VFA-T₂ * T₁ maps were computed from the sliding win

SUBMITTER: Malmberg MA 

PROVIDER: S-EPMC10872756 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature