Early life adversity and substance use: The mediating role of mood and the moderating role of impulsivity.

ABSTRACT:

Introduction

Early life adversity (ELA) is a risk factor for substance use and misuse, and multiple factors mediate and moderate this association. We examined whether moods mediate the relationships between ELA and nicotine use, cannabis use, and co-use, and whether these mediation effects varied as a function of delay discounting.

Methods

A total of 2555 adults completed a delay discounting task and responded to questions related to demographics, ELA, mood, and substance use. Data were analyzed using Pearson correlations and moderated mediation using Hayes' PROCESS macro (V3.4, Model 15).

Results

ELA was positively associated with cannabis use, nicotine use, co-use of both substances, depressed and stressed moods, and it was negatively associated with positive mood.

SUBMITTER: al'Absi M 

PROVIDER: S-EPMC10872790 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature