A thalamo-parietal cortex circuit is critical for place-action coordination.

ABSTRACT: The anterior and lateral thalamus (ALT) contains head direction cells that signal the directional orientation of an individual within the environment. ALT has direct and indirect connections with the parietal cortex (PC), an area hypothesized to play a role in coordinating viewer-dependent and viewer-independent spatial reference frames. This coordination between reference frames would allow an individual to translate movements toward a desired location from memory. Thus, ALT-PC functional connectivity would be critical for moving toward remembered allocentric locations. This hypothesis was tested in rats with a place-action task that requires associating an appropriate action (left or right turn) with a spatial location. There are four arms, each offset by 90°, positioned around a central

SUBMITTER: Simmons CM 

PROVIDER: S-EPMC10872801 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature