Three-dimensional super resolution ultrasound imaging with a multi-frequency hemispherical phased array.

ABSTRACT:

Background

High resolution imaging of the microvasculature plays an important role in both diagnostic and therapeutic applications in the brain. However, ultrasound pulse-echo sonography imaging the brain vasculatures has been limited to narrow acoustic windows and low frequencies due to the distortion of the skull bone, which sacrifices axial resolution since it is pulse length dependent.

Purpose

To overcome the detect limit, a large aperture 256-module sparse hemispherical transmit/receive array was used to visualize the acoustic emissions of ultrasound-vaporized lipid-coated decafluorobutane nanodroplets flowing through tube phantoms and within rabbit cerebral vasculature in vivo via passive acoustic mapping and super resolution techniques.

Methods

Nanodroplets wer

SUBMITTER: Deng L 

PROVIDER: S-EPMC10872837 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature