Economic Modeling Analysis of an Intensive GDMT Optimization Program in Hospitalized Heart Failure Patients.

ABSTRACT:

Background

The STRONG-HF trial (Safety, Tolerability and Efficacy of Up-Titration of Guideline-Directed Medical Therapies for Acute Heart Failure) demonstrated substantial reductions in the composite of mortality and morbidity over 6 months among hospitalized patients with heart failure (HF) who were randomized to intensive guideline-directed medical therapy (GDMT) optimization compared with usual care. Whether an intensive GDMT optimization program would be cost-effective for patients with HF with reduced ejection fraction is unknown.

Methods

Using a 2-state Markov model, we evaluated the effect of an intensive GDMT optimization program on hospitalized patients with HF with reduced ejection fraction. Two population models were created to simulate this intervention, a clinic

SUBMITTER: Dixit NM 

PROVIDER: S-EPMC10872946 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature